The purpose of the study is to provide pilot data on the clinical situations in which ordering a 18F-DCFPyL positron emission tomography/computed tomography (PET/CT) was thought to be clinically useful, and to document how the results of the 18F-DCFPyL PET/CT affected patient management. The results of this study could then serve as a guide to help OHIP to consider these scenarios when deciding the precise indications for funded 18F-DCFPyL PET/CT scans in the future. In this study we will image subjects with prostate cancer using 18F-DCFPyL PET/CT and record how the result of the study affected patient management. Upon finalizing the study protocol in collaboration with the study team at Hamilton Health Sciences and receiving the Health Canada approval to start recruitment, the study was activated in August 2018. To date seven patients have been enrolled in the study. The collaboration between Grand River Hospital and McMaster department of Nuclear Medicine has been extremely successful for a smooth enrollment of patients, execution of PET Scans, and flow of data. The impression from the Radiation Oncologists at Grand River Hospital is that these scans have been tremendously helpful in guiding the treating radiation oncologists and surgeons in their management. Patients found to have no signs of hematogenous spread on PSMA PET have all been treated confidently with curative-intent.